Biological properties of secondary metabolites:
Vol. 2 (2024), Artigos
Vol. 2 (2024)

Biological properties of secondary metabolites: : state of art

Artigos
https://doi.org/10.5281/zenodo.14641742
Published 2024-12-30
Higo José Neri da Silva
Federal University of São Paulo
https://orcid.org/0000-0003-2089-4147
Deylane Menezes Teles Oliveira
Rede Nortesde de Biotecnologia - RENORBIO
Andressa Silva de Mesquita
Laboratório Central de Saúde Pública de Pernambuco
Artigo de Revisão (Português (Brasil))

Keywords

metabólitos secundários
plantas medicinales;
antioxidantes

How to Cite

Silva, H. J. N. da, Oliveira, D. M. T., & Mesquita, A. S. de. (2024). Biological properties of secondary metabolites: : state of art. Innovatio&Science Journal, 2(1). https://doi.org/10.5281/zenodo.14641742
ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver

Download Citation

Endnote/Zotero/Mendeley (RIS) BibTeX

Abstract

Medicinal plants are valued globally for their secondary metabolites, compounds of special interest due to their diverse biological activities and potential applications in sectors such as pharmaceuticals, food and agronomy. Secondary metabolites such as tannins, flavonoids and coumarins stand out for their therapeutic properties, including antioxidant, anti-inflammatory and antitumor activities. Tannins are known for their astringent and therapeutic functions in gastrointestinal treatments, while flavonoids offer antioxidant and cardiovascular benefits, being essential for the prevention of chronic diseases. Anthocyanins, a type of flavonoid, are notable for their antioxidant properties that contribute to cardiovascular health and disease prevention. Isoflavones, found in soy, are studied for their anticancer effects and benefits in hormone replacement therapy. Research on these metabolites is crucial for the development of new therapeutic applications and advances in several scientific and industrial areas, reinforcing the importance of secondary metabolites of medicinal plants in the global health and technology scenario.

https://doi.org/10.5281/zenodo.14641742
Artigo de Revisão (Português (Brasil))

References

1. Silva LR, Oliveira AA, Lima RA. Identificação dos metabólitos secundários do extrato etanólico das folhas de Schinus terebinthifolius Raddi. South American Jouranl of Basic Education, Technical and Technological. 2015;2(2):84-93.

2. Pereira RJ, Cardoso MG. Metabólitos secundários vegetais e benefícios antioxidantes. J Biotec Biodivers. 2012;3(4):146-152.

3. Lima Neto GA, Kaffashi S, Luiz WT, Ferreira WR, Silva YSA, Pazin GV, Violante IMP. Quantificação de metabólitos secundários e avaliação da atividade antimicrobiana e antioxidante de algumas plantas selecionadas do Cerrado de Mato Grosso. Rev Bras Pl Med. 2015;17(4):1069-1077.

4. Cozzolino SMF. Biodisponibilidade de nutrientes. 5ª ed. São Paulo: Manole; 2019.

5. Araújo JM. Química de alimentos: teoria e prática. 5ª ed. Viçosa: Editora UFV; 2019.

6. Cunha AP, Salgueiro L, Roque OR. Metilxantinas. In: Cunha AP, editor. Farmacognosia e fitoquímica. 4ª ed. Lisboa: Fundação Calouste Gulbenkian; 2019.

7. Liu R, Hu Y, Li J, Lin Z. Production of soybean isoflavone genistein in non-legume plants via genetically modified secondary metabolism pathways. Metabolic Engineering. 2018;12(1):58-64.

8. Leite JPV. Fitoterapia: bases científicas e tecnológicas. 2ª ed. São Paulo: Atheneu; 2020.

9. Mesquita AKF, Machado KC, Nunes LCC, Moraes J, Freitas RM. Estudo prospectivo tecnológico e científico do potencial antischistosoma mansoni da cumarina e do ácido o-hidroxicinâmico. Cadernos de Prospecção. 2020;13(1):386-397.

10. Foley S, Navaratnam S, McGarvey DJ, Land EJ, Truscott G, Rice-Evans CA. Singlet oxygen quenching and the redox properties of hydroxycinnamic acids. Free Radical Biology & Medicine. 2019;66:256-263.

11. Schenkel EP, Gosmann G, Athayde ML. Saponinas. In: Simões CM, Schenkel EP, Gosmann G, Mello JCP, Mentz LA, Petrovick PR, editors. Farmacognosia: da planta ao medicamento. 7ª ed. Porto Alegre: Ed. UFRGS/Ed. UFSC; 2021.

12. Wina E, Muetzel S, Becker K. The impact of saponins or saponin-containing plant materials on ruminant production - a review. Journal of Agricultural and Food Chemistry. 2020;68(21):8093–8105.

13. Pizarro APB, Filho AMO, Parente JP, Melo MTV, Santos CE, Lima PR. O aproveitamento do resíduo da indústria do sisal no controle de larvas de mosquitos. Rev Soc Bras Med Trop. 2022;55(1):23-29.

14. Francis G, Kerem Z, Makkar HPS, Becker K. The biological action of saponins in animal systems: a review. British Journal of Nutrition. 2022;127(4):587-605.

15. Pelletier SW. Alkaloids: Chemical and Biological Perspectives. Vol. 20. New York: Wiley; 2020.

16. Lopes GC, Marques JP. Alcaloides como agentes antitumorais: Considerações químicas e biológicas. Revista UNINGÁ Review. 2020;29(1):56-61.

17. Passos CS, Arbo MD, Rates SMK, Poser GL. Terpenóides com atividade sobre o Sistema Nervoso Central (SNC). Revista Brasileira de Farmacognosia. 2020;30;140-149.

18. De Bona AP, Batitucci MCP, Andrade MA, Riva JAR, Perdigão TL. Estudo fitoquímico e análise mutagênica das folhas e inflorescências de Erythrina mulungu (Mart. ex Benth.) através do Teste de Micronúcleo em roedores. Rev Bras Pl Med. 2021;23(2):344-351.